GERMAN TOWN, Md., Sept. 17, 2011 - With a patient's own adult stem cells, there is new
hope for the intractable autoimmune disease lupus - systemic lupus
erythematosus (SLE) - which is difficult to cure.
RNL BIO's research team led by Dr. Jeong-Chan Ra collaborated with a research institute led by Dr. Eun-Hwa Choi
from Samsung Bioscience Research Institute of Samsung Medical Center on
a study on lupus using fat-derived stem cells. Through this study, it
was confirmed that intravenous administration of adult stem cells
restores lupus to normal bodily functions. The findings of this study
were publicized in the famous global research journal, Arthritis and Rheumatism (Impact factor: 8.435) on September 15, 2011.
Model mice were injected with human fat stem cells intravenously in
this study. These model mice demonstrated increased survival as well as
improvement in clinical symptoms. Furthermore, a decrease in antinuclear
antibodies were exhibited in these mice.
Stem cell treatment is more effective in early detection of lupus
symptoms. These model mice were administered with stem cells repeatedly
throughout the course of one year. Although human stem cells were given
to these animals to suppress the immune system, no side effects
appeared.
Lupus occurs in every 75 per 1 million people. There is no cure for
SLE and symptoms can be controlled only temporarily through steroids or
immunosuppressive drugs. This debilitating disease is painful and
unbearable. Some patients with lupus have suicidal thoughts due to its
life-threatening symptoms. Recently, a female patient with lupus who was
known as the "joyful evangelist" committed suicide from the immense
pain.
Dr. Jeong Chan Ra stated, "Based on
this study, diseases that are difficult to treat, such as lupus have
much potential to be treated through stem cell injection. We will
further our research to find ways to cure chronic diseases."
Additional information regarding this study on stem cell treatment for lupus is available online (Arthritis & Rheumatism).
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